Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
1990-10-16
pubmed:abstractText
Vascular casts were prepared using Batson Anatomical corrosion compound, from maximally dilated rat tibialis anterior (TA), extensor digitorum longus (EDL) and soleus (SOL) with normal and limited blood supply (unilateral ligation of the common iliac artery). The weight of casts was expressed as a percentage of muscle wet weight. This value was considered representative for the size of the vascular bed. The value was 2.9 +/- 0.12% (mean +/- SEM) in normal TA, 3.37 +/- 0.15% in EDL and 4.8 +/- 0.43% in SOL. The weight of vascular casts decreased in all muscles to 40% of the values found in the contralateral muscles one week after ligation. Five weeks after ligation, it was about 60% of the control values in TA and EDL, and 80% in SOL. Treatment with torbafylline for one week did not change the weight of the vascular casts. After five weeks the size of the vascular bed was back to control values in EDL and SOL, and only 20% lower than control muscles in TA. This could be attributed to improved development of collateral circulation. Treatment with pentoxifylline improved collateral circulation only in SOL.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0025-7850
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
165-80
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Collateral circulation in skeletal muscles: effect of pentoxifylline and torbafylline.
pubmed:affiliation
Department of Physiology, University of Birmingham, England.
pubmed:publicationType
Journal Article