Linked Life Data

2397722

Source:http://linkedlifedata.com/resource/pubmed/id/2397722

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1990-10-16
pubmed:abstractText
Studies were carried out on the influence of bioshik (tinidazol), synthesised and produced by NPSK of Pharmacy at the Medical Academy on reproduction of male and female rats. The experiments were undertaken after oral administration of bioshik in two doses of 100 mg and 300 mg/kg of body mass (1/20 and 1/10 of LD50) at several stages: I stage during natal application, respectively: 1. during sexual maturation and 2. during the period of sexual maturity and II stage during prenatal administration of bioshik. The studies of the second stage were performed on 3-months old male and female rats, a generation of animals, treated with bioshik during pregnancy. The following parameters were determined: sexual receptivity, reproduction, percentage of early resorptions and mean number of normally implanted fetuses. The described data showed that there was inhibition of sexual receptivity as well as of reproduction after usage of higher doses of 300 mg/kg of body mass only natally and more manifested after application during sexual maturation. There were no data on impairement of the examined parameters for reproduction in offsprings after treatment of pregnant rats with bioshik.
pubmed:language
bul
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0367-0643
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
53-7
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
[Experimental research on the effect of bioshik (tinidazole) on reproduction indices].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract, Case Reports