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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1990-10-12
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pubmed:abstractText |
A paediatric case of lipoprotein glomerulopathy, a new kidney disease characterized by glomerular lipoprotein thrombi, is reported. The patient had massive proteinuria from the age of 8 years, when the nephrotic syndrome was first detected. This was resistant to conventional treatment for more than 10 years. During the course of the disease, the hyperlipidaemia characteristic of hyper-pre-beta-lipoproteinaemia and elevation of apoprotein E persisted, and renal function gradually deteriorated. The renal histopathological findings from four biopsies were essentially the same, with storage of beta-lipoprotein in dilated, balloon-like glomerular capillary lumina. However, the number of glomeruli showing global sclerosis increased and tubulo-interstitial changes progressed in parallel with the gradual clinical deterioration. As in other cases reported in Japan some familial involvement has been noted.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0931-041X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
122-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2397177-Apolipoproteins E,
pubmed-meshheading:2397177-Child,
pubmed-meshheading:2397177-Humans,
pubmed-meshheading:2397177-Hyperlipoproteinemia Type IV,
pubmed-meshheading:2397177-Kidney Diseases,
pubmed-meshheading:2397177-Kidney Glomerulus,
pubmed-meshheading:2397177-Lipoproteins,
pubmed-meshheading:2397177-Male,
pubmed-meshheading:2397177-Microscopy, Electron,
pubmed-meshheading:2397177-Nephrotic Syndrome,
pubmed-meshheading:2397177-Time Factors
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pubmed:year |
1990
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pubmed:articleTitle |
Long-term follow-up of a paediatric case of lipoprotein glomerulopathy.
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pubmed:affiliation |
Department of Paediatrics, St. Marianna University School of Medicine, Kanagawa, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports
|