Linked Life Data

2395842

Source:http://linkedlifedata.com/resource/pubmed/id/2395842

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1990-10-10
pubmed:abstractText
Experiments on 5 test and 16 control Wistar-Kyoto rats have shown that streptozocin diabetes mellitus complicated by proteinuria is characterized by the following changes of the fatty acid spectrum of platelet phospholipids: a decrease in the content of C18:2p6, C18:3p3, C20:4p6, C20:3p9, C20:5p3, in the sum of fatty acids of the linoleic group and the ratio of unsaturated/saturated fatty acids and an increase in the content of C18:0, C20:2p6 and C20:3p6. These changes were accompanied by an increase in the platelet aggregation ability, an increase in their synthesis of thromboxane A2 and a decrease in the synthesis of prostacyclin I2 by vascular endothelium and account for them, to a certain degree. The obtained results are promising with relation to achieving a positive effect of the diets, rich in linoleic acid, for prophylaxis of vascular complications in diabetes mellitus.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0375-9660
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
76-81
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:articleTitle
[Tha fatty acid spectrum of the thrombocyte phospholipids in experimental diabetes mellitus complicated by proteinuria].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract