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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1990-10-4
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pubmed:abstractText |
The present study was undertaken to determinate whether immunosuppression, induced by perioperative allogenic whole-blood transfusions (AWBTs), adversely affects prognosis after total resection of laryngeal cancer by promoting the appearance of recurrences. We studied 62 patients, aged 37-82 years with TNM stage III and IV (UICC, 1987) laryngeal cancer treated between 1977 and 1983. AWBTs were administered to 30/62 patients perioperatively. All patients were followed up for 4 years. After 4 years we found the following disease-free survival indexes: transfused, 12/30 (40%); nontransfused, 22/32 (70%; p less than 0.05). On the base of these dates, we conclude that AWBTs exert a significant influence on early recurrence and on survival in patients with laryngeal cancer.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0301-1569
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
260-4
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2392289-Adult,
pubmed-meshheading:2392289-Aged,
pubmed-meshheading:2392289-Aged, 80 and over,
pubmed-meshheading:2392289-Blood Transfusion,
pubmed-meshheading:2392289-Humans,
pubmed-meshheading:2392289-Immune Tolerance,
pubmed-meshheading:2392289-Intraoperative Period,
pubmed-meshheading:2392289-Laryngeal Neoplasms,
pubmed-meshheading:2392289-Male,
pubmed-meshheading:2392289-Middle Aged,
pubmed-meshheading:2392289-Neoplasm Recurrence, Local,
pubmed-meshheading:2392289-Postoperative Period
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pubmed:year |
1990
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pubmed:articleTitle |
Influence of perioperative transfusion therapy on the recurrence potential of locally advanced laryngeal carcinoma.
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pubmed:affiliation |
II Clinica Otorinolaringoiatrica, Università degli Studi di Torino, Italia.
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pubmed:publicationType |
Journal Article
|