Linked Life Data

2392119

Source:http://linkedlifedata.com/resource/pubmed/id/2392119

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1990-10-2
pubmed:abstractText
The genotoxic potential of endosulfan was assessed in mouse germ cells by 2 in vivo tests: the dominant lethal and the sperm shape abnormality test. At higher doses, endosulfan induced dominant lethal mutations in one mating interval (36-42 days) post treatment. A statistically significant dose-dependent increase in sperm abnormalities was observed with endosulfan treatment. At high doses the sperm count decreased up to 39%. No change in sperm motility was observed at any dose level. On the basis of the present in vivo results, it appears that endosulfan has a damaging effect on spermatogonial cells as well as on sperm morphology.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0027-5107
pubmed:author
pubmed:issnType
Print
pubmed:volume
242
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Studies on the genotoxicity of endosulfan, an organochlorine insecticide, in mammalian germ cells.
pubmed:affiliation
Environmental Microbiology Section, Industrial Toxicology Research Center, Mahatma Gandhi Marg, Lucknow, India.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't