| pubmed-article:2391608 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2391608 | lifeskim:mentions | umls-concept:C0021289 | lld:lifeskim |
| pubmed-article:2391608 | lifeskim:mentions | umls-concept:C0031327 | lld:lifeskim |
| pubmed-article:2391608 | lifeskim:mentions | umls-concept:C0013030 | lld:lifeskim |
| pubmed-article:2391608 | lifeskim:mentions | umls-concept:C0010340 | lld:lifeskim |
| pubmed-article:2391608 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:2391608 | pubmed:dateCreated | 1990-10-3 | lld:pubmed |
| pubmed-article:2391608 | pubmed:abstractText | Dopamine pharmacokinetics was investigated in 14 critically ill newborn infants ranging from 27 to 43 weeks of gestational age and from 0.9 to greater than 4 kg birth weight. Plasma clearance rate was determined from dopamine levels during controlled infusions under actual clinical conditions. Dopamine was administered in stepwise increasing doses up to 8 micrograms/kg/min. Dopamine concentration and dopamine clearance rate were determined from duplicate samples drawn during each infusion in each patient. Steady-state plasma dopamine concentrations and plasma clearance rates were observed within 20 minutes at each infusion. Plasma dopamine concentration ranged from 0.5 ng/ml before infusion to almost 70 ng/ml at an infusion rate of 4 to 8 micrograms/kg/min. There was a linear correlation between infusion rate and plasma dopamine concentration (r = 0.68, p less than 0.001). Neither plasma dopamine concentration nor infusion rate had a significant effect on clearance rate. These data are consistent with first-order kinetics for administered dopamine in critically ill neonates over the range of concentrations studied. | lld:pubmed |
| pubmed-article:2391608 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2391608 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2391608 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2391608 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:2391608 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2391608 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:2391608 | pubmed:issn | 0022-3476 | lld:pubmed |
| pubmed-article:2391608 | pubmed:author | pubmed-author:MartinezA MAM | lld:pubmed |
| pubmed-article:2391608 | pubmed:author | pubmed-author:BaylenB GBG | lld:pubmed |
| pubmed-article:2391608 | pubmed:author | pubmed-author:PolkD HDH | lld:pubmed |
| pubmed-article:2391608 | pubmed:author | pubmed-author:PadburyJ FJF | lld:pubmed |
| pubmed-article:2391608 | pubmed:author | pubmed-author:AgataYY | lld:pubmed |
| pubmed-article:2391608 | pubmed:author | pubmed-author:HabibD MDM | lld:pubmed |
| pubmed-article:2391608 | pubmed:author | pubmed-author:LudlowJ KJK | lld:pubmed |
| pubmed-article:2391608 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2391608 | pubmed:volume | 117 | lld:pubmed |
| pubmed-article:2391608 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2391608 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2391608 | pubmed:pagination | 472-6 | lld:pubmed |
| pubmed-article:2391608 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:2391608 | pubmed:meshHeading | pubmed-meshheading:2391608-... | lld:pubmed |
| pubmed-article:2391608 | pubmed:meshHeading | pubmed-meshheading:2391608-... | lld:pubmed |
| pubmed-article:2391608 | pubmed:meshHeading | pubmed-meshheading:2391608-... | lld:pubmed |
| pubmed-article:2391608 | pubmed:meshHeading | pubmed-meshheading:2391608-... | lld:pubmed |
| pubmed-article:2391608 | pubmed:meshHeading | pubmed-meshheading:2391608-... | lld:pubmed |
| pubmed-article:2391608 | pubmed:meshHeading | pubmed-meshheading:2391608-... | lld:pubmed |
| pubmed-article:2391608 | pubmed:meshHeading | pubmed-meshheading:2391608-... | lld:pubmed |
| pubmed-article:2391608 | pubmed:meshHeading | pubmed-meshheading:2391608-... | lld:pubmed |
| pubmed-article:2391608 | pubmed:meshHeading | pubmed-meshheading:2391608-... | lld:pubmed |
| pubmed-article:2391608 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2391608 | pubmed:articleTitle | Pharmacokinetics of dopamine in critically ill newborn infants. | lld:pubmed |
| pubmed-article:2391608 | pubmed:affiliation | Department of Pediatrics, Harbor-UCLA Medical Center, University of California, Los Angeles School of Medicine, Torrance 90509. | lld:pubmed |
| pubmed-article:2391608 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2391608 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2391608 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2391608 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2391608 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2391608 | lld:pubmed |
