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rdf:type |
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|
lifeskim:mentions |
|
|
pubmed:issue |
5
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pubmed:dateCreated |
1975-11-8
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pubmed:abstractText |
The solid inlet mass spectra of the N-oxide and N-oxide sulphoxide metabolites of promazine, chlorpromazine and methotrimeprazine have been determined at different temperatures and compared with the mass spectra of the main thermolytic product of the N-oxides and N-oxide sulphoxides obtained during combined gas chromatography-mass spectrometry. Diagnostic ions were produced by direct insertion of the compounds at ambient temperature into the mass spectrometer. These ions distinguish the N-oxides of arylalkyl tertiary amines from the N-oxygenated derivatives of primary and secondary arylalkylamines.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
May
|
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pubmed:issn |
0022-3573
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
27
|
|
pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
334-42
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:239134-Chlorpromazine,
pubmed-meshheading:239134-Chromatography, Gas,
pubmed-meshheading:239134-Chromatography, Thin Layer,
pubmed-meshheading:239134-Cyclic N-Oxides,
pubmed-meshheading:239134-Cyclic S-Oxides,
pubmed-meshheading:239134-Mass Spectrometry,
pubmed-meshheading:239134-Methotrimeprazine,
pubmed-meshheading:239134-Phenothiazines,
pubmed-meshheading:239134-Promazine
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|
pubmed:year |
1975
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|
pubmed:articleTitle |
Metabolism of phenothiazines: identification of N-oxygenated products by gas chromatography and mass spectrometry.
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pubmed:publicationType |
Journal Article
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