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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1990-9-27
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pubmed:abstractText |
Mycoplasma membrane protein (MMP) augmented HIV production from MOLT-4 cells chronically infected by HIV. A nearly 3-fold increase of HIV p24 antigen was detected in MMP-treated culture as compared to control culture at 100 micrograms/ml. MMP also augmented HIV production in different T cells chronically infected by HIV-1 and ARV-1. Kinetic experiment showed that HIV production was maximally elevated 24 hr after exposure to MMP. Similarly, MMP also augmented HIV-induced cell fusion and virus production in coculture. Hybridization experiment revealed that this augmentation was due to enhancement of HIV transcription.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0006-291X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
16
|
pubmed:volume |
170
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1365-70
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2390096-Antibodies, Monoclonal,
pubmed-meshheading:2390096-Cell Line,
pubmed-meshheading:2390096-HIV Antigens,
pubmed-meshheading:2390096-HIV-1,
pubmed-meshheading:2390096-Humans,
pubmed-meshheading:2390096-Membrane Proteins,
pubmed-meshheading:2390096-Mycoplasma,
pubmed-meshheading:2390096-T-Lymphocytes,
pubmed-meshheading:2390096-Tumor Necrosis Factor-alpha,
pubmed-meshheading:2390096-Virus Replication
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pubmed:year |
1990
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pubmed:articleTitle |
Mycoplasma can enhance HIV replication in vitro: a possible cofactor responsible for the progression of AIDS.
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pubmed:affiliation |
Department of Virology and Parasitology, Yamaguchi University School of Medicine, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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