|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
1990-9-27
|
|
pubmed:abstractText |
Eighteen influenza A (H3N2) viruses were isolated during a single outbreak in a closed community of Carmelite nuns. Serological analysis of the virus haemagglutinin (HAs), using a panel of monoclonal antibodies, demonstrated antigenic microheterogeneity. In contrast, no significant biochemical differences were detected in viral genes by RNA:RNA hybridisation or in structural or nonstructural polypeptides analysed by high-resolution polyacrylamide gel electrophoresis (PAGE) or by limited proteolysis followed by PAGE. Influenza A (H3N2) viruses isolated in the vicinity of the convent were distinguishable from each other and from the epidemic viruses isolated in the convent both antigenically and biochemically.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0146-6615
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
31
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
112-9
|
|
pubmed:dateRevised |
2005-12-5
|
|
pubmed:meshHeading |
pubmed-meshheading:2388044-Adult,
pubmed-meshheading:2388044-Antigenic Variation,
pubmed-meshheading:2388044-Antigens, Viral,
pubmed-meshheading:2388044-Disease Outbreaks,
pubmed-meshheading:2388044-Female,
pubmed-meshheading:2388044-Genes, Viral,
pubmed-meshheading:2388044-Hemagglutinin Glycoproteins, Influenza Virus,
pubmed-meshheading:2388044-Hemagglutinins, Viral,
pubmed-meshheading:2388044-Humans,
pubmed-meshheading:2388044-Influenza, Human,
pubmed-meshheading:2388044-Influenza A Virus, H3N2 Subtype,
pubmed-meshheading:2388044-Influenza A virus,
pubmed-meshheading:2388044-RNA, Viral,
pubmed-meshheading:2388044-Rome,
pubmed-meshheading:2388044-Social Isolation,
pubmed-meshheading:2388044-Viral Structural Proteins
|
|
pubmed:year |
1990
|
|
pubmed:articleTitle |
Genome and antigenic analysis of influenza A (H3N2) viruses isolated from an epidemic in a closed community of Carmelite nuns.
|
|
pubmed:affiliation |
Division of Virology, Istituto Superiore di Sanita, Rome, Italy.
|
|
pubmed:publicationType |
Journal Article
|
