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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1990-9-26
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pubmed:abstractText |
The susceptibility of 234 Bacteroides non-fragilis strains and 56 fusobacteria from 12 European centers to amoxicillin, amoxicillin/clavulanate, ticarcillin, ticarcillin/clavulanate, cefoxitin, imipenem and metronidazole was tested and related to beta-lactamase production. Beta-lactamase production was detected in 42.3 % of the Bacteroides strains and 26.8% of the fusobacteria. The MIC90 of amoxicillin for beta-lactamase-negative strains was 0.5 microgram/ml and the MIC90 of ticarcillin 2.0 micrograms/ml. In the case of beta-lactamase-positive strains the MIC90 of amoxicillin (32 micrograms/ml) and ticarcillin (16 micrograms/ml) dropped to less than or equal to 1.0 microgram/ml upon addition of clavulanate; 65.8% of these strains were susceptible to amoxicillin and 98.2% to ticarcillin, but all were susceptible when clavulanate was added. All strains were susceptible to imipenem and metronidazole, and 99.3% to cefoxitin.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Amoxicillin,
http://linkedlifedata.com/resource/pubmed/chemical/Cefoxitin,
http://linkedlifedata.com/resource/pubmed/chemical/Clavulanic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Clavulanic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Drug Combinations,
http://linkedlifedata.com/resource/pubmed/chemical/Imipenem,
http://linkedlifedata.com/resource/pubmed/chemical/Metronidazole,
http://linkedlifedata.com/resource/pubmed/chemical/Ticarcillin
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0934-9723
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
417-21
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pubmed:dateRevised |
2000-12-18
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pubmed:meshHeading |
pubmed-meshheading:2387295-Amoxicillin,
pubmed-meshheading:2387295-Bacteroides,
pubmed-meshheading:2387295-Cefoxitin,
pubmed-meshheading:2387295-Clavulanic Acid,
pubmed-meshheading:2387295-Clavulanic Acids,
pubmed-meshheading:2387295-Drug Combinations,
pubmed-meshheading:2387295-Fusobacterium,
pubmed-meshheading:2387295-Imipenem,
pubmed-meshheading:2387295-Metronidazole,
pubmed-meshheading:2387295-Microbial Sensitivity Tests,
pubmed-meshheading:2387295-Ticarcillin
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pubmed:year |
1990
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pubmed:articleTitle |
Susceptibility of Bacteroides non-fragilis and fusobacteria to amoxicillin, amoxicillin/clavulanate, ticarcillin, ticarcillin/clavulanate, cefoxitin, imipenem and metronidazole.
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pubmed:affiliation |
Department of Pathology (Clinical Microbiology), Case Western Reserve University, Cleveland, Ohio 44106.
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pubmed:publicationType |
Journal Article
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