Linked Life Data

2386932

Source:http://linkedlifedata.com/resource/pubmed/id/2386932

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
17
pubmed:dateCreated
1990-9-27
pubmed:abstractText
The relationship between smoking habits and the risk of renal cell carcinoma was investigated in a case-control study conducted in northern Italy on 131 cases of histologically confirmed cancers of the renal parenchyma (85 males, 46 females) and 394 controls in hospital for acute, nonneoplastic, nonurological disorders. Compared with never smokers, the relative risk (RR) was 1.7 (95% confidence interval = 1.0-3.1) among ex-smokers. A direct and significant dose-risk relationship was observed among current smokers, with RR of 1.1, 1.9, and 2.3 for moderate, intermediate, and heavy smokers. This trend in risk was statistically significant (chi2(1) = 5.04; P = 0.02). The risk was directly related to duration of smoking (RR = 1.7 for less than 30 versus 1.8 for greater than or equal to 30 years, P = 0.04), and inversely with age at starting (RR = 2.0 for less than or equal to 20 versus 1.7 for greater than 20 years) and, among ex-smokers, with time elapsed since stopping (RR = 2.2 for less than 10 versus 1.3 for greater than or equal to 10 years). This pattern of risk, together with the absence of appreciable confounding, adds further evidence for a causal nature of the association between smoking and renal cell cancer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0008-5472
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5231-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Smoking and renal cell carcinoma.
pubmed:affiliation
Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't