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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1990-9-20
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pubmed:abstractText |
The regulatory effect of 2,3-DPG on oxygen transport and binding to hemoglobin was analyzed. Under conditions of substitution hemodilution by isooncotic 3.4% Rheodextran (Spofa), changes in the content of 2,3-DPG in arterial and venous blood were enzymatically determined over several days. Reference values of 2,3-DPG were obtained in the studied series of dogs (2.05 +/- 0.74 x 10(-6) mol.ml-1 in whole blood 4.69 +/- 1.52 x 10(-6) mol.g-1 of erythrocyte volume, and 13.39 +/- 2.82 x 10(-6) mol.ml-1 of hemoglobin). In anesthetized animals the content of 2,3-DPG in arterial blood was significantly higher (6.28 +/- 0.84 x 10(-6) mol.ml-1 of erythrocyte volume) than in venous blood (6.01 +/- 0.80 x 10(-6) mol.ml-1 of erythrocyte volume). At substitution hemodilution the 2,3-DPG content in erythrocytes of venous blood decreased from 5.46 +/- 0.67 to 4.97 +/- 1.31 x 10(-6) mol.ml-1 of erythrocyte volume. The subsequent increase to 6.04 +/- 0.71 x 10(-6) mol.ml-1 of erythrocyte volume was achieved by nonlinear increase over the following days, at persisting low hemoglobin content in blood.
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pubmed:language |
slo
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0006-9248
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
386-90
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:2383774-2,3-Diphosphoglycerate,
pubmed-meshheading:2383774-Animals,
pubmed-meshheading:2383774-Blood Substitutes,
pubmed-meshheading:2383774-Diphosphoglyceric Acids,
pubmed-meshheading:2383774-Dogs,
pubmed-meshheading:2383774-Erythrocytes,
pubmed-meshheading:2383774-Female,
pubmed-meshheading:2383774-Hemodilution,
pubmed-meshheading:2383774-Hemoglobins,
pubmed-meshheading:2383774-Humans,
pubmed-meshheading:2383774-Male
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pubmed:year |
1990
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pubmed:articleTitle |
[The physiologic significance of 2,3-diphosphoglycerate and changes in its erythrocyte levels in an experiment].
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pubmed:affiliation |
Katedry fyziológie LFUK, Bratislava.
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pubmed:publicationType |
Journal Article,
English Abstract
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