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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1990-9-17
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pubmed:abstractText |
The analgesic and antiinflammatory activities of some N,N'-bis(2-hydroxybenzoyl)-diaminoalkanes 3 a-l were studied. The compounds were prepared very conveniently by fusion of phenyl salicylate 2 and diaminoalkanes 1 a-l. The pharmacological activities were influenced by the number of carbon atoms in the polimethylenic chain. Some derivatives were more effective and less gastrolesive than salicylamide.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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|
pubmed:status |
MEDLINE
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pubmed:month |
Mar
|
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pubmed:issn |
0014-827X
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
45
|
|
pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
285-92
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:2383344-Analgesics,
pubmed-meshheading:2383344-Animals,
pubmed-meshheading:2383344-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:2383344-Behavior, Animal,
pubmed-meshheading:2383344-Chemical Phenomena,
pubmed-meshheading:2383344-Chemistry,
pubmed-meshheading:2383344-Diamines,
pubmed-meshheading:2383344-Hydroxybenzoic Acids,
pubmed-meshheading:2383344-Lethal Dose 50,
pubmed-meshheading:2383344-Male,
pubmed-meshheading:2383344-Mice,
pubmed-meshheading:2383344-Rats,
pubmed-meshheading:2383344-Rats, Inbred Strains,
pubmed-meshheading:2383344-Stomach Ulcer
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pubmed:year |
1990
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pubmed:articleTitle |
Synthesis and evaluation of the analgesic and antiinflammatory activities of N,N'-bis(2-hydroxybenzoyl)-diaminoalkanes.
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pubmed:affiliation |
Dipartimento di Chimica e Tecnologie Farmaceutiche, Università di Parlermo.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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