Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1990-9-7
pubmed:abstractText
Pulmonary function testing was conducted consecutively in 29 healthy men (age range, 42 to 71 years) undergoing elective coronary artery bypass grafting. Lung volumes, expiratory flow rates, diffusing capacity, and blood gases were determined before operation, at discharge (8.7 +/- 1.9 days), and at 3 months postoperatively. In addition, peak expiratory flow rate was measured immediately after extubation (21.4 +/- 2.7 hours). Fifteen patients had smoked within the past year, but none had a history of pulmonary impairment. Twenty-two patients had internal mammary artery (IMA) dissection. Operation and recovery were uneventful in all cases. After extubation, peak expiratory flow rate was decreased by 65%. At discharge, lung volumes were decreased by 19% to 33% below preoperative values and expiratory flow rates were decreased by 33% to 37% below preoperative values. Some minor changes were detected at 3 months. Further analysis of these changes according to smoking history, age, preoperative weight, dissection of IMA, and aortic cross-clamp time showed that only IMA dissection affected the postextubation changes in peak expiratory flow rate (p less than 0.0001), whereas the decreases in functional residual capacity and expiratory reserve volume at discharge were affected by IMA dissection (p less than 0.05) and age (p = 0.01). Thus, median sternotomy is associated with severe but short-term pulmonary dysfunction; IMA dissection has a significant adverse effect on these changes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0003-4975
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
268-73
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Determinants of pulmonary function in patients undergoing coronary bypass operations.
pubmed:affiliation
Department of Surgery, Medical Center of Delaware, Wilmington 19713.
pubmed:publicationType
Journal Article