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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
16
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pubmed:dateCreated |
1990-9-13
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pubmed:abstractText |
Seven cases of gastric B-cell low-grade lymphomas were characterized by morphology, immunohistology and electron microscopy. All them were immunophenotyped with a panel of monoclonal antibodies against immunoglobulins and other B-cell determinants. Histologic study of gastric B-cell low-grade lymphomas showed germinal centers of lobated shape and polyclonal nature, mainly polyclonal subepithelial plasma cell (except in one case) and neoplastic interfollicular B-cells of monoclonal character. Light-chain restriction supports the neoplastic nature of gastric lymphoma of low-grade malignancy, a distinctive tumour of extranodal B-cell origin. Interfollicular B-cells share with marginal zone cells a perifollicular localization, morphology and phenotype, suggesting a possible relation between these two cellular subtypes. In two cases, the tumour appears constituted by monocytoid B-lymphocytes (MBL), which suggests a relation of tumoral interfollicular B-cells with this subpopulation.
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pubmed:language |
spa
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0025-7753
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
28
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pubmed:volume |
94
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
601-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2381244-Adult,
pubmed-meshheading:2381244-Antibodies, Monoclonal,
pubmed-meshheading:2381244-B-Lymphocytes,
pubmed-meshheading:2381244-Female,
pubmed-meshheading:2381244-Gastric Mucosa,
pubmed-meshheading:2381244-Humans,
pubmed-meshheading:2381244-Lymphoid Tissue,
pubmed-meshheading:2381244-Lymphoma,
pubmed-meshheading:2381244-Male,
pubmed-meshheading:2381244-Microscopy, Electron,
pubmed-meshheading:2381244-Middle Aged,
pubmed-meshheading:2381244-Neoplasm Staging,
pubmed-meshheading:2381244-Stomach Neoplasms
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pubmed:year |
1990
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pubmed:articleTitle |
[Low-grade B cell gastric lymphoma originated in mucosa-associated lymphoid tissue. Relationship of tumor cells with the marginal zone and monocytoid B lymphocytes. An immunohistochemical and ultrastructural study].
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pubmed:affiliation |
Servicio de Anatomía Patológica, Hospital Virgen de la Salud, Toledo.
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pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
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