| pubmed-article:2380383 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2380383 | lifeskim:mentions | umls-concept:C0040944 | lld:lifeskim |
| pubmed-article:2380383 | lifeskim:mentions | umls-concept:C0002679 | lld:lifeskim |
| pubmed-article:2380383 | lifeskim:mentions | umls-concept:C0332325 | lld:lifeskim |
| pubmed-article:2380383 | lifeskim:mentions | umls-concept:C0450254 | lld:lifeskim |
| pubmed-article:2380383 | pubmed:issue | 7 | lld:pubmed |
| pubmed-article:2380383 | pubmed:dateCreated | 1990-9-12 | lld:pubmed |
| pubmed-article:2380383 | pubmed:abstractText | Trichosporon beigelii caused fatal disseminated infections that were resistant to amphotericin B in two granulocytopenic patients. In vitro susceptibility studies demonstrated that both index strains of T. beigelii were inhibited but not killed by amphotericin B at achievable concentrations in serum. The minimum lethal concentration for both isolates was greater than or equal to 18 micrograms/ml. Five of seven other isolates were found to have a similar pattern of amphotericin B resistance. The fact that the minimum lethal concentration of T. beigelii was many times greater than its MIC was consistent with a resistance pattern of tolerance. We concluded that T. beigelii may be resistant in vitro to amphotericin B and that this in vitro resistance was correlated with refractory, disseminated trichosporonosis in granulocytopenic patients. T. beigelii should be included in the expanding list of amphotericin B-resistant fungi. | lld:pubmed |
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| pubmed-article:2380383 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2380383 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2380383 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2380383 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2380383 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:2380383 | pubmed:issn | 0095-1137 | lld:pubmed |
| pubmed-article:2380383 | pubmed:author | pubmed-author:LeeJJ | lld:pubmed |
| pubmed-article:2380383 | pubmed:author | pubmed-author:WalshT JTJ | lld:pubmed |
| pubmed-article:2380383 | pubmed:author | pubmed-author:RubinMM | lld:pubmed |
| pubmed-article:2380383 | pubmed:author | pubmed-author:PizzoP APA | lld:pubmed |
| pubmed-article:2380383 | pubmed:author | pubmed-author:KellyPP | lld:pubmed |
| pubmed-article:2380383 | pubmed:author | pubmed-author:RinaldiM GMG | lld:pubmed |
| pubmed-article:2380383 | pubmed:author | pubmed-author:MelcherG PGP | lld:pubmed |
| pubmed-article:2380383 | pubmed:author | pubmed-author:McGoughD ADA | lld:pubmed |
| pubmed-article:2380383 | pubmed:author | pubmed-author:CallenderDD | lld:pubmed |
| pubmed-article:2380383 | pubmed:author | pubmed-author:LeccionesJJ | lld:pubmed |
| pubmed-article:2380383 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2380383 | pubmed:volume | 28 | lld:pubmed |
| pubmed-article:2380383 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2380383 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2380383 | pubmed:pagination | 1616-22 | lld:pubmed |
| pubmed-article:2380383 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:2380383 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2380383 | pubmed:articleTitle | Trichosporon beigelii, an emerging pathogen resistant to amphotericin B. | lld:pubmed |
| pubmed-article:2380383 | pubmed:affiliation | Infectious Diseases Section, National Cancer Institute, Bethesda, Maryland 20892. | lld:pubmed |
| pubmed-article:2380383 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2380383 | pubmed:publicationType | Case Reports | lld:pubmed |
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