Linked Life Data

2379557

Source:http://linkedlifedata.com/resource/pubmed/id/2379557

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1990-9-7
pubmed:abstractText
The basal forebrain has been implicated in the regulation of generalized motor convulsive activity particularly from amygdala kindling. The effect of electrical stimulation of the substantia innominata and ventral pallidal regions of the basal forebrain in rats with acute interictal penicillin foci in the frontal parietal neocortex was determined. Stimulation of this area resulted in generalized cortical EEG synchronization, an inconsistent effect on interictal spike frequency, and generalized seizures that were not prevented by atropine. The results support a role for these basal forebrain structures in the regulation of generalized seizures from a cortical focus mediated primarily through influences on thalamocortical pathways.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0014-4886
pubmed:author
pubmed:issnType
Print
pubmed:volume
109
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
237-42
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Secondary generalization of seizures from a cortical penicillin focus following stimulation of the basal forebrain.
pubmed:affiliation
Department of Clinical Neurological Sciences, University Hospital, London, Ontario, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't