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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1990-9-10
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pubmed:abstractText |
Over 500,000 cholecystectomies are performed each year in the United States. The procedure has its risks (mortality is 1.2% in the general population and 3% in patients aged 75 years or over) and it is expensive: the average direct cost of each cholecystectomy is about $10,000, for a national total of $5 billion annually. An alternative to surgery is to dissolve the stone with ursodiol, a naturally occurring bile acid, which has been successfully used for cholesterol gallstones with a diameter less than 20 mm. A computer model was developed to compare the costs of surgery for gallstones and treatment with ursodiol. In a hypothetical health maintenance organization with one million enrollees, use of ursodiol treatment rather than cholecystectomy would result in cumulative savings of $8.5 million after one year, $30.7 million after five years, and $57.8 million after ten years.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0149-2918
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
250-62
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2379230-Cholecystectomy,
pubmed-meshheading:2379230-Cholelithiasis,
pubmed-meshheading:2379230-Computer Simulation,
pubmed-meshheading:2379230-Costs and Cost Analysis,
pubmed-meshheading:2379230-Deoxycholic Acid,
pubmed-meshheading:2379230-Humans,
pubmed-meshheading:2379230-Ursodeoxycholic Acid
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pubmed:articleTitle |
A computer model for evaluating the costs of cholecystectomy or ursodiol treatment in the management of cholelithiasis.
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pubmed:affiliation |
PharmaServe, Glen Oaks, New York.
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pubmed:publicationType |
Journal Article
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