Linked Life Data

2374989

Source:http://linkedlifedata.com/resource/pubmed/id/2374989

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1990-8-28
pubmed:abstractText
Leakage from colonic anastomoses is a common cause of morbidity in patients recovering from bowel surgery. We evaluated a technique of laser-fibrinogen reinforcement to strengthen colonic anastomoses in a canine model. After creation of eight single-layer interrupted suture anastomoses in six dogs, indocyanine green-dye-enhanced fibrinogen was topically applied to the serosal surface and exposed to 808 nm diode laser energy. Immediately following colonic anastomosis, the mean leakage pressure was 137 +/- 22 mm Hg in the group (n = 8) using sutures alone and 326 +/- 67 mm Hg (P less than 0.001) in the group (n = 8) after the sutured anastomosis was reinforced with lasered-fibrinogen. On histological examination, no evidence of thermal injury to the tissue edges was noted and a layer of fibrinogen bridged the anastomotic gap. Laser dye-enhanced fibrinogen reinforcement significantly enhances the strength of sutured colonic anastomoses without causing appreciable thermal injury to the host tissues.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0930-2794
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
97-9
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Canine colonic anastomoses reinforced with dye-enhanced fibrinogen and a diode laser.
pubmed:affiliation
Department of Surgery, Columbia University College of Physicians & Surgeons, New York, New York.
pubmed:publicationType
Journal Article