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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1990-8-23
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pubmed:abstractText |
To determine the most suitable vaccination schedule in developing countries, a study was conducted to reevaluate the immunogenicity of monovalent measles vaccine and trivalent measles-mumps-rubella vaccine at different ages. The success rate of measles vaccination was 84% at 9 months, 88% at 12 months and 100% at 15 months of age. Vaccination with measles vaccines at 9 and 15 months of age was also 96% immunogenic. Most vaccinees (16 of 17) not responding to the first measles vaccine before 1 year of age developed measles antibody with another shot of vaccine after 15 months of age. Trivalent measles-mumps-rubella vaccine worked well in children ages 14 to 18 months. Administering trivalent vaccine and hepatitis B vaccine concurrently at 1 year of age, rubella and mumps antibodies developed in more than 95% of vaccinees, while measles antibody was detected in 88%. Responses to hepatitis B vaccine in this situation were good; 89% of vaccinees developed antibody against hepatitis B surface antigen (greater than or equal to 10 mIU/ml) and the geometric mean titer was 362.49 mIU/ml. In summary vaccination twice at 9 and 15 months is effective and is a useful regimen in developing countries where measles is still endemic. Trivalent vaccine and hepatitis B vaccine will not interfere with each other when given together at 1 year of age.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0891-3668
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
461-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2371079-Age Factors,
pubmed-meshheading:2371079-Antibodies, Viral,
pubmed-meshheading:2371079-Developing Countries,
pubmed-meshheading:2371079-Drug Evaluation,
pubmed-meshheading:2371079-Drug Interactions,
pubmed-meshheading:2371079-Hepatitis B,
pubmed-meshheading:2371079-Humans,
pubmed-meshheading:2371079-Immunization Schedule,
pubmed-meshheading:2371079-Infant,
pubmed-meshheading:2371079-Measles,
pubmed-meshheading:2371079-Mumps,
pubmed-meshheading:2371079-Prospective Studies,
pubmed-meshheading:2371079-Rubella,
pubmed-meshheading:2371079-Taiwan,
pubmed-meshheading:2371079-Vaccination,
pubmed-meshheading:2371079-Viral Vaccines
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pubmed:year |
1990
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pubmed:articleTitle |
Effect of monovalent measles and trivalent measles-mumps-rubella vaccines at various ages and concurrent administration with hepatitis B vaccine.
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pubmed:affiliation |
Department of Pediatrics, National Taiwan University Hospital, Taipei, Republic of China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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