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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1990-8-16
|
| pubmed:abstractText |
Thirty-one cases of thyroid malignancies which were originally classified as anaplastic carcinoma were reexamined immunohistochemically using PAP methods (peroxidase:antiperoxidase) for IgM, IgG, IgA, cytokeratin, calcitonin, lysozyme and alpha-1-antitrypsin. The reclassification results were compared with patient data such as clinical symptoms, treatment modalities, and clinical outcome. Postoperative radiotherapy was carried out in more than 80% of cases, chemotherapy in none. Seven of 31 tumors showed a positive staining for IgM (n = 4), IgG (n = 2), and IgA (n = 1) antibodies. All of these cases were negative for epithelial markers. Surprisingly, not only all small cell tumors (n = 3) but also 4 tissues with predominantly giant cell areas were among those reclassified as primary malignant lymphoma.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0364-2313
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
14
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
291-4; discussion 295
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:2368431-Carcinoma,
pubmed-meshheading:2368431-Diagnosis, Differential,
pubmed-meshheading:2368431-Follow-Up Studies,
pubmed-meshheading:2368431-Humans,
pubmed-meshheading:2368431-Immunohistochemistry,
pubmed-meshheading:2368431-Lymphoma,
pubmed-meshheading:2368431-Prognosis,
pubmed-meshheading:2368431-Thyroid Neoplasms
|
| pubmed:articleTitle |
Immunohistochemical reclassification of anaplastic carcinoma reveals small and giant cell lymphoma.
|
| pubmed:affiliation |
Department of Surgery, University of Heidelberg, Federal Republic of Germany.
|
| pubmed:publicationType |
Journal Article
|