Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1990-8-14
pubmed:abstractText
Controlled clinical studies represent an important tool for quantifying the effects of air pollutants. Examinations can be carried out with the aid of exposure chambers, or employing inhalation via a mask. To date, pulmonary function tests have been the major means of establishing the effects of pollutants. Studies performed to date have served to identify high-risk groups, to demonstrate dose-effect relationships, and to examine borderline values. It is probable that pulmonary function tests are not suitable for detecting the influence of some of the environmental pollutants. More recent clinical techniques, such as broncho-alveolar lavage, nasal lavage, the measurement of alveolar permeability with the aid of labelled aerosols, represent possibilities for investigating other pollutant-induced effects. We need clinical studies because, over and beyond the traditional methods of epidemiology and animal experiments, they can contribute important aspects of the estimation of the risks of environmental pollutants.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0934-8387
pubmed:author
pubmed:issnType
Print
pubmed:volume
44 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
399-402
pubmed:dateRevised
2009-4-7
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
[Why do we need controlled clinical studies?].
pubmed:affiliation
University of Rochester, NY.
pubmed:publicationType
Journal Article, Comparative Study, English Abstract