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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1990-8-8
|
| pubmed:abstractText |
We investigated prospectively in 128 patients (140 eyes) the role of six routine clinical tests in the differentiation of ischemic central retinal vein occlusion (CRVO) from non-ischemic CRVO during its early acute phase. There were four functional tests [visual acuity, visual fields, relative afferent pupillary defect (RAPD), electroretinography (ERG)] and two morphologic tests (ophthalmoscopy and fluorescein fundus angiography). We found that none of the six tests had 100% sensitivity and specificity in such a differentiation during the early, acute phase, so that no one test can be considered a "gold standard"; however, combined information from all six is almost always reliable. Overall, the four functional tests proved far superior to the two morphologic tests in differentiating ischemic from non-ischemic CRVO:RAPD was most reliable in uniocular CRVO (with a normal fellow eye), followed closely by ERG in all cases; combined information from RAPD and ERG differentiated 97% of cases; perimetry was the next most reliable, followed by visual acuity. The two morphologic tests performed worst; fluorescein angiography provided either no information at all on retinal capillary nonperfusion (in at least one-third of the eyes during the early, acute phase) because of multiple limitations, or sometimes provided misleading information. Ophthalmoscopic appearance is the least reliable, most misleading parameter.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0721-832X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
228
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
201-17
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:2361592-Acute Disease,
pubmed-meshheading:2361592-Aged,
pubmed-meshheading:2361592-Aged, 80 and over,
pubmed-meshheading:2361592-Diagnosis, Differential,
pubmed-meshheading:2361592-Electroretinography,
pubmed-meshheading:2361592-Fluorescein Angiography,
pubmed-meshheading:2361592-Follow-Up Studies,
pubmed-meshheading:2361592-Fundus Oculi,
pubmed-meshheading:2361592-Humans,
pubmed-meshheading:2361592-Ischemia,
pubmed-meshheading:2361592-Middle Aged,
pubmed-meshheading:2361592-Ophthalmoscopy,
pubmed-meshheading:2361592-Predictive Value of Tests,
pubmed-meshheading:2361592-Prospective Studies,
pubmed-meshheading:2361592-Pupil Disorders,
pubmed-meshheading:2361592-Retinal Diseases,
pubmed-meshheading:2361592-Retinal Vein Occlusion,
pubmed-meshheading:2361592-Retinal Vessels,
pubmed-meshheading:2361592-Visual Acuity,
pubmed-meshheading:2361592-Visual Fields
|
| pubmed:year |
1990
|
| pubmed:articleTitle |
Differentiation of ischemic from non-ischemic central retinal vein occlusion during the early acute phase.
|
| pubmed:affiliation |
Department of Ophthalmology, University of Iowa, Iowa City 52242.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|