Linked Life Data

2358196

Source:http://linkedlifedata.com/resource/pubmed/id/2358196

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1990-8-1
pubmed:abstractText
Estrogen vaginal cream was given to 10 postmenopausal women with a diagnosis of genuine stress urinary incontinence. Clinical evaluation and urethral cytology from the midurethra were performed before and after 6 weeks of estrogen treatment. A favorable clinical response was obtained in 50% of the treated patients, in whom signs and symptoms of incontinence disappeared or significantly improved, by subjective and objective evaluation. Cytologic changes at the midurethra correlated well with clinical response to estrogens. Patients with a favorable response to treatment showed a positive 'maturation index' of squamous epithelium, changing towards more intermediate and superficial cells, and less transitional cells (p less than 0.05). Patients with a poor clinical response to estrogens had no significant change in urethral cytology after 6 weeks of therapy. Our results suggest that improvement or cure of stress incontinence after estrogen administration in postmenopausal women is achieved by affecting the 'urethral mucosal factor'.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0378-7346
pubmed:author
pubmed:issnType
Print
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
211-3
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Changes in urethral cytology following estrogen administration.
pubmed:affiliation
Department of Obstetrics and Gynecology, University of Southern California School of Medicine, Los Angeles.
pubmed:publicationType
Journal Article