Linked Life Data

2357521

Source:http://linkedlifedata.com/resource/pubmed/id/2357521

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1990-7-31
pubmed:abstractText
DDT, 1,1,1-trichloro-2,2-bis(p-chlorophenyl)-ethane is one of the best-known insecticides which produces neurotoxic syndrome in mammals. DDT is also a world-wide environmental contaminant which is still used in several countries. We have previously reported on pronounced retention of DDT in the neonatal mouse brain. We have also observed that DDT and a DDT metabolite, DDOH, conjugated to palmitic acid (DDOH-PA), which have been found in DDT-treated female rats, affect the muscarinic cholinergic receptors in the brain of the neonatal mouse. We now report that neonatal exposure to a single low oral dose of DDT and DDOH-PA (1.4 mumol/kg b.wt.) also can lead to a permanent hyperactive condition in the mice as adults.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
23
pubmed:volume
514
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
141-2
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Altered behaviour in adult mice exposed to a single low dose of DDT and its fatty acid conjugate as neonates.
pubmed:affiliation
Department of Zoophysiology, Uppsala University, Sweden.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't