Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1 Suppl
pubmed:dateCreated
1990-7-23
pubmed:abstractText
State health departments are increasingly faced with the task of responding to reports of apparent cancer and other disease clusters. Since 1979, 141 requests for investigation have been received by the Wisconsin Division of Health, with over 60% of these requests occurring since 1985. Mounting public concern and limited resources have resulted in the development of a "disease cluster investigation and analysis protocol." Protocol steps include: 1) circumscribing the cluster; 2) ascertaining cases; 3) assessing risk of the exposed versus a referent population; 4) statistically analyzing disease rates; 5) examining potential exposure; 6) assessing biologic plausibility; 7) determining cluster significance and need for further investigation; and 8) reporting results. To demonstrate the protocol, the authors present a case example of an investigation of an apparent cancer cluster. Since 1979, 62 reports were resolved with initial contact with informant education (step 1), 61 reports required descriptive analysis (steps 1-8) with no site visit, and 18 reports required site visits. None of the reports required further in-depth epidemiologic investigation. This protocol provides a systematic approach to investigation and analysis, prioritizes the need for more in-depth study, and, when necessary, assuages community concerns when a disease cluster is reported.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0002-9262
pubmed:author
pubmed:issnType
Print
pubmed:volume
132
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S14-22
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed-meshheading:2356826-Adolescent, pubmed-meshheading:2356826-Adult, pubmed-meshheading:2356826-Aged, pubmed-meshheading:2356826-Causality, pubmed-meshheading:2356826-Child, pubmed-meshheading:2356826-Child, Preschool, pubmed-meshheading:2356826-Clinical Protocols, pubmed-meshheading:2356826-Cluster Analysis, pubmed-meshheading:2356826-Diffusion of Innovation, pubmed-meshheading:2356826-Environmental Exposure, pubmed-meshheading:2356826-Female, pubmed-meshheading:2356826-Health Status Indicators, pubmed-meshheading:2356826-Humans, pubmed-meshheading:2356826-Infant, pubmed-meshheading:2356826-Infant, Newborn, pubmed-meshheading:2356826-Male, pubmed-meshheading:2356826-Middle Aged, pubmed-meshheading:2356826-Neoplasms, pubmed-meshheading:2356826-Public Health, pubmed-meshheading:2356826-Wisconsin
pubmed:year
1990
pubmed:articleTitle
State health department response to disease cluster reports: a protocol for investigation.
pubmed:affiliation
Section of Environmental and Chronic Disease Epidemiology, Wisconsin Department of Health and Social Services, Madison 53701-0309.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.