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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1990-7-26
|
| pubmed:abstractText |
Between August 1, 1982, and December 31, 1988, 487 patients with clinically established or suspected diagnosis of a hereditary degenerative or dystrophic disorder of the ocular fundus or of a disorder of the optic pathways were evaluated with an extensive set of clinical and electrophysiological tests, 67% of the patients were referred from other eye departments. In order of magnitude the most frequently encountered diagnoses were: 1) 'functional' disturbances (18%), 2) disorders of the optic nerve (9%), 3) retinitis pigmentosa (8%), 4), 5) and 6) progressive cone dystrophy, disorders of the central optic pathways, and fundus flavimaculatus/Stargardt's disease (5% each), and 7) choriocapillaris atrophy (4%). Choriocapillaris atrophy affected older patients than retinitis pigmentosa (P less than 0.001). A male preponderance was observed for juvenile retinoschisis (P less than 0.005) and congenital stationary night blindness (P less than 0.05), and a female dominance in the groups of patients with 'functional' symptoms (P less than 0.01). A specific diagnosis was established in 469 patients. After exclusion of 16 patients referred because of a known hereditary disposition, 196 (43%) of the remaining 453 patients were referred under the same diagnosis as our final diagnosis, 153 (34%) under a different diagnosis and 104 (23%) without any clear diagnosis. Obviously, there is a need for regional centers specialized in these disorders.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0001-639X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
68
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
131-8
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:2356699-Adolescent,
pubmed-meshheading:2356699-Adult,
pubmed-meshheading:2356699-Aged,
pubmed-meshheading:2356699-Aged, 80 and over,
pubmed-meshheading:2356699-Child,
pubmed-meshheading:2356699-Child, Preschool,
pubmed-meshheading:2356699-Choroid Diseases,
pubmed-meshheading:2356699-Color Perception Tests,
pubmed-meshheading:2356699-Dark Adaptation,
pubmed-meshheading:2356699-Electroretinography,
pubmed-meshheading:2356699-Female,
pubmed-meshheading:2356699-Humans,
pubmed-meshheading:2356699-Infant,
pubmed-meshheading:2356699-Male,
pubmed-meshheading:2356699-Middle Aged,
pubmed-meshheading:2356699-Pigment Epithelium of Eye,
pubmed-meshheading:2356699-Retinal Degeneration,
pubmed-meshheading:2356699-Retinal Diseases,
pubmed-meshheading:2356699-Sex Factors,
pubmed-meshheading:2356699-Visual Acuity,
pubmed-meshheading:2356699-Visual Fields
|
| pubmed:year |
1990
|
| pubmed:articleTitle |
Evaluation of patients with obvious or suspected degenerative and dystrophic disorders of the retina, pigment epithelium and choroid. Experience from a Swedish referral center.
|
| pubmed:affiliation |
Department of Ophthalmology, University of Linköping, Sweden.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|