Linked Life Data

2353646

Source:http://linkedlifedata.com/resource/pubmed/id/2353646

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
22
pubmed:dateCreated
1990-7-18
pubmed:abstractText
The acute procedural outcome of percutaneous transluminal coronary angioplasty in 304 patients with unstable angina was retrospectively examined with respect to the influence of prolonged preprocedural intravenous heparin therapy. Clinical and angiographic success in 135 patients receiving heparin therapy for greater than or equal to 24 hours was 91% while such success was noted in 81% of patients not treated with heparin (p = 0.02). The incidence of immediate postprocedural thrombotic vessel occlusion was higher in the nonheparin group than in the heparin-treated group (8.3 vs 1.5%, respectively, p less than 0.01). In addition, the overall rate of thromboembolic target and branch or distal vessel occlusion was 12.4% in the nonheparin group and 1.5% in the heparin-treated group (p less than 0.001). Thus, prolonged preprocedural intravenous heparin administration in this well-defined group of patients with unstable angina resulted in an improved procedural success rate and a significant decrease in the risk of abrupt vessel closure. These observations are concordant with current understanding of the pathophysiology of unstable angina.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0002-9149
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
65
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1425-9
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Influence of heparin therapy on percutaneous transluminal coronary angioplasty outcome in unstable angina pectoris.
pubmed:affiliation
Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia.
pubmed:publicationType
Journal Article