Linked Life Data

2353558

Source:http://linkedlifedata.com/resource/pubmed/id/2353558

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1990-7-19
pubmed:abstractText
Eleven healthy women were examined three times a week during the third trimester. The possibility of monthly cyclical changes in the serum concentrations of cortisol, placental hCG and fetoplacental estradiol was tested because of previous findings of highly significant monthly cycles in aldosterone and progesterone. A semiparametric statistical model was used and a highly significant monthly cycle in serum cortisol was found, whereas the amplitude for a cycle in hCG was barely significant and non-significant for estradiol. The previous findings of monthly cycles in aldosterone and progesterone, using a parametric multivariate model, were retested by the semiparametric method employed for the present publication. The findings of highly significant cycles in aldosterone and progesterone were corroborated. We think that the results indicate the existence of an adrenocortical cycle. We think that the monthly ovarian cycle in the non-pregnant state is paralleled by an adrenocortical cycle, where changes in aldosterone are "linked" with changes in progesterone and changes in cortisol with changes in estrogens. During pregnancy the adrenocortical cycle persists, probably controlled by the maternal hypothalamus. The physiological background for this monthly endocrine cycle during pregnancy is enigmatic.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0001-5598
pubmed:author
pubmed:issnType
Print
pubmed:volume
122
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
617-22
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
A monthly cycle in the adrenocortical function during third trimester pregnancy.
pubmed:affiliation
Department of Clinical Chemistry, Aalborg Hospital, Denmark.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't