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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1990-7-12
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pubmed:abstractText |
One hundred and forty-five first-degree relatives (89 parents [96%] and 56 siblings [98%]) of 46 children and adolescents with severe primary obsessive compulsive disorder (OCD) were personally interviewed with clinical and structured psychiatric interviews. Parent interviews were scored by a rater blind to proband diagnosis. Thirty percent of probands had at least one first-degree relative with OCD: 25% of fathers and 9% of mothers received this diagnosis. Forty-five percent of fathers and 65% of mothers received one or more other psychiatric diagnoses. The increased familial rate of OCD over that expected from a general population, and over that found in parents of conduct disordered patients, is consistent with a genetic factor in OCD. Presenting obsessive compulsive symptoms of probands and their parents were usually dissimilar, arguing against any simple social or cultural transmission.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0890-8567
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
407-12
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2347838-Adolescent,
pubmed-meshheading:2347838-Adult,
pubmed-meshheading:2347838-Child,
pubmed-meshheading:2347838-Female,
pubmed-meshheading:2347838-Humans,
pubmed-meshheading:2347838-Male,
pubmed-meshheading:2347838-Mental Disorders,
pubmed-meshheading:2347838-Middle Aged,
pubmed-meshheading:2347838-Models, Genetic,
pubmed-meshheading:2347838-Obsessive-Compulsive Disorder,
pubmed-meshheading:2347838-Psychiatric Status Rating Scales,
pubmed-meshheading:2347838-Risk Factors
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pubmed:year |
1990
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pubmed:articleTitle |
Psychiatric disorders in first degree relatives of children and adolescents with obsessive compulsive disorder.
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pubmed:affiliation |
Child Psychiatry Branch, NIMH, Bethesda, MD 20892.
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pubmed:publicationType |
Journal Article
|