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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1990-7-3
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pubmed:abstractText |
Thymuses from female (New Zealand black x New Zealand white)F1 [( NZB x NZW]F1), New Zealand black, and New Zealand white mice of different ages were examined by immunohistochemical and flow cytometric analysis. Two-and-a-half-month-old (NZB x NZW)F1 mice showed infiltration of the thymus with B cells, and by 6-8 months of age, showed a disruption of the entire medullary area. More than 80% of the thymic B cells had the phenotypic characteristics of conventional B cells (IgM+, IgD+, Ly-1-). Total lymphoid irradiation induced a marked depletion of medullary B cells and a restoration of the thymic architecture.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0004-3591
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
702-10
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2346525-Animals,
pubmed-meshheading:2346525-B-Lymphocytes,
pubmed-meshheading:2346525-Cell Movement,
pubmed-meshheading:2346525-Cell Separation,
pubmed-meshheading:2346525-Female,
pubmed-meshheading:2346525-Flow Cytometry,
pubmed-meshheading:2346525-Immunohistochemistry,
pubmed-meshheading:2346525-Lymphatic Irradiation,
pubmed-meshheading:2346525-Mice,
pubmed-meshheading:2346525-Mice, Inbred Strains,
pubmed-meshheading:2346525-Thymus Gland
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pubmed:year |
1990
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pubmed:articleTitle |
B cell infiltration of the thymic medulla in New Zealand black, New Zealand white, and (New Zealand black x New Zealand white)F1 mice. Effect of total lymphoid irradiation.
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pubmed:affiliation |
Department of Medicine, Stanford University School of Medicine, California 94305.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|