rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
1990-6-29
|
pubmed:abstractText |
Spleen cells from BALB/c mice previously immunized with B-lymphoblastoid cell line RPMI-1788 were fused with P3-X-63-Ag8.653 myeloma cells. Monoclonal antibodies (Ab) IPO-4 were screened on 18 cell lines by the indirect immuno-fluorescence method. Cryostat sections of tissues were stained according to the PAP technique. The Mab IPO-4 were tested for reactivity with blood cells of 17 healthy persons and 102 patients with chronic lymphocytic leukemia, acute lymphoblastic and myeloblastic leukemias, hairy cell leukemia, multiple myeloma, non-Hodgkin's lymphomas and Hodgkin's disease and mitogen stimulated lymphocytes. MAb IPO-4 were found to be directed against antigen expressed on activated T and B cells.
|
pubmed:language |
rus
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0204-3564
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
12
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
21-4
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:2344819-Animals,
pubmed-meshheading:2344819-Antibodies, Monoclonal,
pubmed-meshheading:2344819-Antigens, Differentiation, B-Lymphocyte,
pubmed-meshheading:2344819-Antigens, Differentiation, T-Lymphocyte,
pubmed-meshheading:2344819-B-Lymphocytes,
pubmed-meshheading:2344819-Cell Line,
pubmed-meshheading:2344819-Humans,
pubmed-meshheading:2344819-Leukemia,
pubmed-meshheading:2344819-Lymphocyte Activation,
pubmed-meshheading:2344819-Lymphoma,
pubmed-meshheading:2344819-Mice,
pubmed-meshheading:2344819-Mice, Inbred BALB C,
pubmed-meshheading:2344819-Multiple Myeloma,
pubmed-meshheading:2344819-T-Lymphocytes,
pubmed-meshheading:2344819-Tumor Markers, Biological
|
pubmed:year |
1990
|
pubmed:articleTitle |
[Monoclonal antibodies IPO-4 recognizing antigen-activated human T and B lymphocytes].
|
pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|