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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
889
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pubmed:dateCreated |
1990-6-28
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pubmed:abstractText |
Interviews were conducted with 101 consecutive adult patients admitted to Wellington Hospital with a diagnosis of asthma to assess the extent to which beta agonist drugs are self-administered by asthmatic patients during severe asthma. The 99 patients prescribed an inhaled beta agonist were subdivided into two groups: group A comprising 79 patients prescribed a beta agonist for inhalation via an inhaler (metered dose aerosol or dry powder device) alone; group B comprising 20 patients prescribed beta agonist for inhalation via both an inhaler and nebuliser. In group A, the attacks of asthma lasted greater than 24 hours in 64/79 patients, and 22% of these patients reported taking more than 60 doses of their inhaler, and 52% more than 30 doses during the 24 hr period prior to admission. In group B, the attacks of asthma lasted greater than 24 h in 17/20 patients, and 35% of these patients self-administered their nebuliser more than six times, and 76% more than four times during the 24 h period prior to admission. In addition to their nebuliser use, these patients also took a median 23 doses of their inhaler during this 24 h period. This use of inhaled beta agonist contrasts with the recommended practice in both the USA and Europe, where most physicians recommend no more than 15 doses of a beta agonist as the maximal dose per day. We conclude that asthmatic patients in New Zealand self-administer high doses of inhaled beta 2 agonist drugs during severe exacerbations of asthma.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
|
pubmed:issn |
0028-8446
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
9
|
pubmed:volume |
103
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
205-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2342689-Adolescent,
pubmed-meshheading:2342689-Adrenal Cortex Hormones,
pubmed-meshheading:2342689-Adult,
pubmed-meshheading:2342689-Aged,
pubmed-meshheading:2342689-Asthma,
pubmed-meshheading:2342689-Female,
pubmed-meshheading:2342689-Fenoterol,
pubmed-meshheading:2342689-Humans,
pubmed-meshheading:2342689-Male,
pubmed-meshheading:2342689-Middle Aged,
pubmed-meshheading:2342689-Nebulizers and Vaporizers,
pubmed-meshheading:2342689-New Zealand,
pubmed-meshheading:2342689-Self Administration,
pubmed-meshheading:2342689-Time Factors
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pubmed:year |
1990
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pubmed:articleTitle |
The self-administration of inhaled beta agonist drugs during severe asthma.
|
pubmed:affiliation |
Department of Medicine, Wellington School of Medicine.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|