Linked Life Data

2341991

Source:http://linkedlifedata.com/resource/pubmed/id/2341991

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1990-6-26
pubmed:abstractText
Extracellular stimulation over the dorsal funiculus in the spinal cord of lampreys was found to selectively activate prolonged episodes of fictive arousal respiration. The induced episodes showed comparable increases in cycle frequency and motoneuron burst duration to the spontaneous arousal pattern observed in isolated brain preparations. Intracellular stimulation of primary sensory neurons with axons in the dorsal funiculus, called 'dorsal cells', also elicited the arousal pattern. Mechanoreceptive dorsal cells respond to cutaneous stimulation. When mechanical stimuli were applied to the skin of intact lampreys or to lampreys with ipsilateral vagotomy, arousal respiration was induced. Bilateral, but not unilateral, trigeminal lesion blocked dorsal cell induction of the arousal response. Spontaneous arousal respiration was recorded from intact, unrestrained lampreys. These results suggest that fictive arousal respiration is the in vitro correlate of natural arousal respiration in lampreys, and that one mechanism leading to arousal respiration may be the activity of sensory dorsal cells. A model for respiratory motor pattern switching in lamprey is proposed. The model suggests that the normal and arousal patterns are produced by separately engaging rostral or caudal pattern generators in the medulla, rather than by modifying one pattern generator.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0340-7594
pubmed:author
pubmed:issnType
Print
pubmed:volume
166
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
675-84
pubmed:dateRevised
2009-6-4
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Control of respiratory motor pattern by sensory neurons in spinal cord of lamprey.
pubmed:affiliation
Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri 63110.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.