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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1990-6-27
|
| pubmed:abstractText |
The bone mineral content (BMC) in patients with insulin-dependent diabetes is reduced by 10% early in the disease, but due to a lack of long-term longitudinal studies it is unknown whether this diabetic osteopenia develops further through life. Over a time period of 11 years we examined the BMC in a group of seven adult insulin-dependent diabetics, in whom physiological and pathological factors affecting bone metabolism had been excluded; the patients were well regulated without diabetic complications. The BMC was not significantly decreased at the initial examination. The longitudinal study revealed a small but statistically significant fall in BMC, mainly in trabecular bone. The narrow (95%) confidence interval of median end value (93.3-99.0% of initial BMC) indicates that the annual decrease in BMC in such patients is of the order of 0.5%, a reduction that is probably clinically insignificant.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0954-6820
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
227
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
325-7
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:2341825-Adult,
pubmed-meshheading:2341825-Bone Density,
pubmed-meshheading:2341825-Bone Diseases, Metabolic,
pubmed-meshheading:2341825-Diabetes Mellitus, Type 1,
pubmed-meshheading:2341825-Female,
pubmed-meshheading:2341825-Humans,
pubmed-meshheading:2341825-Longitudinal Studies,
pubmed-meshheading:2341825-Male
|
| pubmed:year |
1990
|
| pubmed:articleTitle |
Long-term bone loss in insulin-dependent diabetes mellitus.
|
| pubmed:affiliation |
Department of Internal Medicine, Aalborg Hospital, Denmark.
|
| pubmed:publicationType |
Journal Article
|