Linked Life Data

2338256

Source:http://linkedlifedata.com/resource/pubmed/id/2338256

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1990-6-15
pubmed:abstractText
Since the 1940s, the major hypothesis regarding the stimulus for neovascularization occurring in diabetic retinopathy and other "ischemic" retinopathies has involved the release of a soluble angiogenic factor from the ischemic retina. We sought to test this by measuring the endothelial mitogenic activity that could be extracted from an ischemic retina caused by branch vein occlusion in the cat. We found that the extractable endothelial-cell mitogenic activity from normal retinal areas was similar to that in ischemic areas at 1, 2, and 7 days after the occlusion. In the area of occluded veins, the oxygen partial pressure was low (7 +/- 7 mm Hg) compared with the normal value (23 +/- 8 mm Hg). The data did not show any increase in soluble mitogenic factor release from the ischemic retina versus normal retinal areas under the conditions of this experiment.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0721-832X
pubmed:author
pubmed:issnType
Print
pubmed:volume
228
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
191-4
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Capillary endothelial-cell mitogenic activity in experimental branch vein occlusion.
pubmed:affiliation
Duke University Eye Center, Durham, NC 27710.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.