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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1990-6-21
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pubmed:abstractText |
Cytochemical demonstrations of 5'-nucleotidase and alkaline phosphatase reveal the activity of these enzymes on regions of cell apposition from the late four-cell stage onward. These enzyme activities also appear on regions of artificial cell contact between aggregated embryos having more than four cells. Cytochemistry of single two-cell embryos does not reveal 5'-nucleotidase nor alkaline phosphatase activity, however, these enzyme activities appear at both the artificial and natural contacts in chimaeras of two two-cell embryos. We interpret these results as meaning: (1) that cell contact causes the regionalization of 5'-nucleotidase and alkaline phosphatase activity on the cell surface, (2) that these enzyme activities can be induced or enhanced by contact between two two-cell embryos, (3) that a signal is transmitted from the artificial to the natural contact.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0012-1606
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
139
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
363-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2338172-5'-Nucleotidase,
pubmed-meshheading:2338172-Alkaline Phosphatase,
pubmed-meshheading:2338172-Animals,
pubmed-meshheading:2338172-Blastocyst,
pubmed-meshheading:2338172-Cell Aggregation,
pubmed-meshheading:2338172-Cell Communication,
pubmed-meshheading:2338172-Cell Division,
pubmed-meshheading:2338172-Chimera,
pubmed-meshheading:2338172-Cycloheximide,
pubmed-meshheading:2338172-Female,
pubmed-meshheading:2338172-Histocytochemistry,
pubmed-meshheading:2338172-Mice,
pubmed-meshheading:2338172-Mice, Inbred Strains
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pubmed:year |
1990
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pubmed:articleTitle |
Effect of cell contact on regionalization of mouse embryos.
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pubmed:affiliation |
Departamento de Biología, Universidad de Chile, Santiago.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|