Linked Life Data

2338134

Source:http://linkedlifedata.com/resource/pubmed/id/2338134

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1990-6-20
pubmed:abstractText
Heme methyl 1H and 13C resonances of met-cyano form of myoglobin from the shark, Geleorhinus japonicus (GJMbCN), have been assigned via 1H-13C heteronuclear shift correlated spectroscopy (COSY) connectivities and their hyperfine shifts were compared with those of the corresponding resonances of some hemoproteins. Variation of the heme methyl 1H hyperfine shift pattern correlates well with the angle (phi) between the projection of the proximal histidyl imidazole plane onto the heme plane and the NII-Fe-NIV vector. The alteration of the interaction of the heme peripheral side-chains and/or the iron-bound ligand with the surrounding amino acid residues cannot account for large differences in the shifts of the corresponding heme methyl resonances between GJMbCN and sperm whale MbCN. Since the heme methyl 1H shifts for GJMbCN fall in between those of the corresponding resonances for sperm whale Mb and Aplysia limacina Mb in which the phi values have been reported to be 19 degrees and 29 degrees, respectively, the phi value in GJMb is estimated to be slightly larger than 19 degrees.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0014-5793
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
264
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
113-6
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Heme methyl hyperfine shift pattern as a probe for determining the orientation of the functionally relevant proximal histidyl imidazole with respect to the heme in hemoproteins.
pubmed:affiliation
Department of Biomolecular Engineering, Tokyo Institute of Technology, Japan.
pubmed:publicationType
Journal Article