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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1990-6-20
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pubmed:abstractText |
Following daily intraperitoneal injections of ethanol at a dose of 3.5 g/kg rats developed tolerance to its hypnotic action, which was manifested in a drastic decrease of ethanol--induced sleep time and the number of animals sleeping more than 60 min. In the liver, this process was characterized by an elevated alcohol dehydrogenase activity and a decreased aldehyde dehydrogenase one, whereas that of MEOS remained unchanged.
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pubmed:language |
rus
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0365-9615
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
109
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
161-2
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pubmed:dateRevised |
2008-10-8
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pubmed:meshHeading |
pubmed-meshheading:2337652-Acetaldehyde,
pubmed-meshheading:2337652-Alcohol Dehydrogenase,
pubmed-meshheading:2337652-Aldehyde Dehydrogenase,
pubmed-meshheading:2337652-Animals,
pubmed-meshheading:2337652-Drug Tolerance,
pubmed-meshheading:2337652-Ethanol,
pubmed-meshheading:2337652-Injections, Intraperitoneal,
pubmed-meshheading:2337652-Liver,
pubmed-meshheading:2337652-Male,
pubmed-meshheading:2337652-Rats,
pubmed-meshheading:2337652-Sleep
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pubmed:year |
1990
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pubmed:articleTitle |
[System of ethanol and acetaldehyde metabolism in the rat liver during the development of ethanol tolerance].
|
pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|