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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1990-6-12
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pubmed:abstractText |
An in vitro bioassay system was used to study the effects of cyclopiazonic acid (CPA) mycotoxin on cardiac muscle. Acute exposure to 6 micrograms of CPA/ml of modified Krebs-Henseleit solution significantly (P less than 0.05) decreased 5 in vitro turkey cardiac muscle performance criteria: maximal weight a muscle could lift; maximal contraction velocity; relaxation velocity; time to peak contraction; and total time for muscle contraction and relaxation. The effect on these 5 criteria appeared to result from intracellular changes partially associated with calcium availability and were irreversible, suggesting that physiologic changes had developed after acute exposure to CPA.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
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pubmed:issn |
0002-9645
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
51
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
836-8
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:2337289-Animals,
pubmed-meshheading:2337289-Indoles,
pubmed-meshheading:2337289-Muscle Relaxation,
pubmed-meshheading:2337289-Muscles,
pubmed-meshheading:2337289-Mycotoxins,
pubmed-meshheading:2337289-Myocardial Contraction,
pubmed-meshheading:2337289-Papillary Muscles,
pubmed-meshheading:2337289-Time Factors,
pubmed-meshheading:2337289-Turkeys
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pubmed:year |
1990
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pubmed:articleTitle |
In vitro effects of cyclopiazonic acid mycotoxin on turkey papillary muscles.
|
pubmed:affiliation |
USDA, Agricultural Research Service, National Animal Disease Center, Ames, IA 50010.
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pubmed:publicationType |
Journal Article
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