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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1986-6-20
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pubmed:abstractText |
Mitomycin C treatment of Escherichia coli K-12 cells containing the nonconjugative plasmid CloDF13 resulted in inhibition of host chromosome protein synthesis and a high rate of synthesis of two CloDF13-specified proteins whose molecular weights correspond to cloacin and immunity protein. Five molecules of immunity protein were synthesized for each cloacin DF13 molecule. Mitomycin C-treated cells containing a copy mutant of CloDF13 made three to four times as much of each protein as cells containing wild-type CloDF13. CloDF13 plasmids that contained the transposon Tn1 were isolated. Two did not induce after mitomycin C treatment, failing both to inhibit host cell synthesis and to produce the two new proteins. In minicells, they showed reduced CloDF13-specified protein synthesis and produced three Tn1-specified proteins.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/233723-1045010,
http://linkedlifedata.com/resource/pubmed/commentcorrection/233723-1099983,
http://linkedlifedata.com/resource/pubmed/commentcorrection/233723-1107805,
http://linkedlifedata.com/resource/pubmed/commentcorrection/233723-14429601,
http://linkedlifedata.com/resource/pubmed/commentcorrection/233723-16591472,
http://linkedlifedata.com/resource/pubmed/commentcorrection/233723-4338179,
http://linkedlifedata.com/resource/pubmed/commentcorrection/233723-4555406,
http://linkedlifedata.com/resource/pubmed/commentcorrection/233723-4583233,
http://linkedlifedata.com/resource/pubmed/commentcorrection/233723-4588566,
http://linkedlifedata.com/resource/pubmed/commentcorrection/233723-4591959,
http://linkedlifedata.com/resource/pubmed/commentcorrection/233723-4595198,
http://linkedlifedata.com/resource/pubmed/commentcorrection/233723-4616938,
http://linkedlifedata.com/resource/pubmed/commentcorrection/233723-4867749,
http://linkedlifedata.com/resource/pubmed/commentcorrection/233723-5231757,
http://linkedlifedata.com/resource/pubmed/commentcorrection/233723-773363
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0021-9193
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
130
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
846-51
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pubmed:dateRevised |
2010-9-2
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pubmed:meshHeading |
pubmed-meshheading:233723-Bacteriocins,
pubmed-meshheading:233723-Cloacin,
pubmed-meshheading:233723-Colicins,
pubmed-meshheading:233723-DNA Transposable Elements,
pubmed-meshheading:233723-Escherichia coli,
pubmed-meshheading:233723-Kinetics,
pubmed-meshheading:233723-Klebsiella,
pubmed-meshheading:233723-Mitomycin,
pubmed-meshheading:233723-Mitomycins,
pubmed-meshheading:233723-Molecular Weight,
pubmed-meshheading:233723-Mutation,
pubmed-meshheading:233723-Plasmids
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pubmed:year |
1977
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pubmed:articleTitle |
Changes in protein synthesis on mitomycin C induction of wild-type and mutant CloDF13 plasmids.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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