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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1990-6-7
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pubmed:abstractText |
Vitamin K deficiency has been reported in patients who were treated with antibiotics and placed on poor diets after surgery. High-performance liquid chromatography (HPLC) was used to study the influence of dietary intake on vitamin K concentrations in surgical patients (n = 22). Plasma phylloquinone decreased rapidly from 1.19 +/- 0.16 to 0.47 +/- 0.12 nmol/L (means +/- SEM, n = 11) on a low-phylloquinone diet and from 1.16 +/- 0.12 to 0.36 +/- 0.07 nmol/L (n = 11) by postoperative fasting. A small amount of phylloquinone and a large amount of menaquinone were found in liver tissue. Phylloquinone concentration was 28.0 +/- 4.3 pmol/g liver (wet weight) on the standard diet (n = 7) whereas it was 6.8 +/- 1.1 pmol/g on the low-phylloquinone diet after 3 d (n = 8). Because phylloquinone is rapidly depleted by fasting, it may be difficult to prevent vitamin K deficiency by dietary phylloquinone alone during long-term fasting after surgery.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0002-9165
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
51
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
846-52
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2333843-Adult,
pubmed-meshheading:2333843-Aged,
pubmed-meshheading:2333843-Chromatography, High Pressure Liquid,
pubmed-meshheading:2333843-Fasting,
pubmed-meshheading:2333843-Female,
pubmed-meshheading:2333843-Humans,
pubmed-meshheading:2333843-Intraoperative Period,
pubmed-meshheading:2333843-Liver,
pubmed-meshheading:2333843-Male,
pubmed-meshheading:2333843-Middle Aged,
pubmed-meshheading:2333843-Postoperative Period,
pubmed-meshheading:2333843-Preoperative Care,
pubmed-meshheading:2333843-Vitamin K,
pubmed-meshheading:2333843-Vitamin K Deficiency
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pubmed:year |
1990
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pubmed:articleTitle |
Vitamin K concentrations in the plasma and liver of surgical patients.
|
pubmed:affiliation |
Second Department of Surgery, Faculty of Medicine, Kyoto University, Japan.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Controlled Clinical Trial
|