Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1990-6-5
pubmed:abstractText
Cellular and humoral immune responses were assessed in 24 patients with systemic sclerosis and matched controls by immunization with a thymus dependent (TD) antigen, keyhole limpet hemocyanin (KLH), a and thymus independent (TI) antigen, dinitrophenylated Ficoll (DNP-Ficoll). Cell mediated immunity in the patients with systemic sclerosis expressed as delayed cutaneous hypersensitivity to KLH, as well as the primary T dependent and T independent antibody responses were normal. Our findings suggest that there is no generalized defect in the immune responsiveness of patients with systemic sclerosis. There is however evidence that specific defects may occur in certain subsets of patients with systemic sclerosis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0315-162X
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
323-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Normal immune responses in systemic sclerosis.
pubmed:affiliation
Department of Rheumatology, West Middlesex University Hospital, Isleworth, London, England.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't