Linked Life Data

2330788

Source:http://linkedlifedata.com/resource/pubmed/id/2330788

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1990-5-29
pubmed:abstractText
Retrograde tracing with true blue (TB) and diamidino yellow (DY) was used to determine the topography of the peripheral projections of the trigeminal (V) ganglion in rats on embryonic day 16 (E-16; E-0 was the day of conception). On E-16, the earliest age at which we were able to accomplish retrograde tracing successfully, the topographic organization of the V ganglionic projection to the periphery was quite adult-like. Cells projecting to the vibrissa pad were restricted to the ophthalmic-maxillary portion of the ganglion, with those innervating dorsal row follicles located medially and those supplying ventral row follicles located laterally. Injections of tracer into ophthalmic skin and/or the cornea labeled cells that were tightly clustered in the most dorsal and anteromedial portion of the ophthalmic-maxillary region. Injections of tracer into the lower jaw or the skin just rostral to the ear labeled cells that were restricted to the lateral, mandibular part of the ganglion. None of the combinations of injections we carried out resulted in large numbers of double-labeled V ganglion cells. Injection of TB into the vibrissa pad and DY into the upper lip produced a small number of double-labeled ganglion cells. This was also the case for paired injections of TB and DY into the lower jaw and lip, respectively. No more than 15 such cells were observed in a ganglion. These findings suggest that the substantial cell death that has been reported to occur in prenatal V ganglion development (Davies and Lumsden, 1984) is probably not involved in the correction of major peripheral targeting errors by the axons of V ganglion cells.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0899-0220
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
67-84
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Topographic organization of the peripheral projections of the trigeminal ganglion in the fetal rat.
pubmed:affiliation
Department of Anatomy, Medical College of Ohio, Toledo 43699.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.