Linked Life Data

2329090

Source:http://linkedlifedata.com/resource/pubmed/id/2329090

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
1990-5-29
pubmed:abstractText
Endocochlear potentials (EPs) were investigated in healthy guinea pigs and in those exposed to white noise of 125 dB SPL for 20-80 min. EPs were measured during and after temporary anoxia (3.5 min, denoted as reversible anoxia) and then during continuous anoxia to evaluate noise-induced changes in EP properties. Succino-dehydrogenase (SDH) activity and morphologic changes in hair cells were also evaluated in surface preparations of the hair cells. It was found that changes in EPs correlated with the duration of noise exposure. The longer the noise exposure, the greater the decrease in EPs. EPs could recover in one week post-exposure, in roughly the same time needed for recovery of SDH activity in hair cells. Noise exposure also resulted in some changes in EP dynamic behaviour during and after reversible anoxia, but did not cause any significant change in maximal negative EP. The mechanisms underlying these results are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0378-5955
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
143-9
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Changes in endocochlear potential during anoxia after intense noise exposure.
pubmed:affiliation
Fundamental Medical Department, Nanjing Railway Medical College, China.
pubmed:publicationType
Journal Article