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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1990-5-18
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pubmed:abstractText |
A lymphocyte transformation test (LTT) was able to distinguish between nickel-sensitive subjects and non-nickel-sensitive controls. Sixty-one out of 66 (92%) nickel-sensitive subjects had positive stimulation indices in 6- and/or 7-day assays using 5 micrograms/ml of nickel sulphate, whereas none of the 43 controls gave positive results. Stimulation indices were not enhanced by the patch testing of subjects to nickel before performing the LTT. A weak correlation was seen between the results of the LTT and the macroscopic degree of patch-test reactivity. The concentration of nickel sulphate used (5 micrograms/ml) did not have a significant non-specific mitogenic effect.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0007-0963
|
pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
122
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
293-8
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2322494-Adult,
pubmed-meshheading:2322494-Dermatitis, Contact,
pubmed-meshheading:2322494-Female,
pubmed-meshheading:2322494-Humans,
pubmed-meshheading:2322494-Irritants,
pubmed-meshheading:2322494-Lymphocyte Activation,
pubmed-meshheading:2322494-Male,
pubmed-meshheading:2322494-Nickel,
pubmed-meshheading:2322494-Patch Tests
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pubmed:year |
1990
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pubmed:articleTitle |
The discrimination between nickel-sensitive and non-nickel-sensitive subjects by an in vitro lymphocyte transformation test.
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pubmed:affiliation |
University Department of Dermatology, Royal Infirmary, Edinburgh.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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