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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1990-5-21
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pubmed:abstractText |
Maximal individual [3H]corticosterone binding capacity in the hippocampus was lower in C57BL/6 mice than in BALB/c mice, and positively correlated with active avoidance learning in the two strains. Moreover, a parallel difference in the activity of hypothalamo-pituitary adrenocortical axis (HPAA) was found, consisting in a level of plasma corticosterone in C57BL/6 higher than in BALB/c mice. These results confirm the genetically determined differences in behavior of C57BL/6 and BALB/c mice, and demonstrate their association with differences in hippocampal corticosterone binding capacity, pointing to a functional relationship between the behavioral and neuroendocrine parameters.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0166-4328
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
5
|
pubmed:volume |
37
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
185-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2322415-Animals,
pubmed-meshheading:2322415-Avoidance Learning,
pubmed-meshheading:2322415-Corticosterone,
pubmed-meshheading:2322415-Hippocampus,
pubmed-meshheading:2322415-Male,
pubmed-meshheading:2322415-Mice,
pubmed-meshheading:2322415-Mice, Inbred BALB C,
pubmed-meshheading:2322415-Mice, Inbred C57BL,
pubmed-meshheading:2322415-Receptors, Glucocorticoid,
pubmed-meshheading:2322415-Receptors, Steroid,
pubmed-meshheading:2322415-Species Specificity
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pubmed:year |
1990
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pubmed:articleTitle |
Strain-dependent differences in hippocampal glucocorticoid binding capacity and active avoidance in the mouse.
|
pubmed:affiliation |
Instituto di Farmacologia 2a, Medical Faculty, University of Rome, La Sapienza, Italy.
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pubmed:publicationType |
Journal Article,
Comparative Study
|