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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1990-4-26
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pubmed:abstractText |
During succinylcholine-induced muscle fasciculations, gastroesophageal barrier pressure in fasted adult dogs (n = 10) was compared by esophageal manometry with that in the same dogs with full stomachs. After fasting, fasciculations did not increase significantly either mean intragastric pressure (4.7 +/- 1.3 mm Hg before; 5.2 +/- 1.7 mm Hg during) or lower esophageal sphincter pressure (35.4 +/- 21.4 mm Hg before; 40.6 +/- 17.5 mm Hg during). Filling the dogs' stomachs with 300 mL of saline significantly increased both mean intragastric pressure (from 3.8 +/- 2.2 to 7.4 +/- 1.4 mm Hg) and mean lower esophageal sphincter pressure (from 20.2 +/- 6.8 to 28.6 +/- 14.8 mm Hg). Fasciculations did not produce a further increase in either mean intragastric or mean lower esophageal sphincter pressure. Most importantly, in all animals, under all conditions, gastroesophageal barrier pressure remained positive (range, 6.0-65.5 mm Hg) and therefore served as a barrier to passive regurgitation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0003-2999
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
70
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
420-3
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:2316884-Animals,
pubmed-meshheading:2316884-Dogs,
pubmed-meshheading:2316884-Esophagogastric Junction,
pubmed-meshheading:2316884-Fasciculation,
pubmed-meshheading:2316884-Manometry,
pubmed-meshheading:2316884-Muscle Relaxation,
pubmed-meshheading:2316884-Pressure,
pubmed-meshheading:2316884-Stomach,
pubmed-meshheading:2316884-Succinylcholine
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pubmed:year |
1990
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pubmed:articleTitle |
Lower esophageal sphincter integrity is maintained during succinylcholine-induced fasciculations in dogs with "full" stomachs.
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pubmed:affiliation |
Department of Anesthesiology, University of Florida College of Medicine, Gainesville.
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pubmed:publicationType |
Journal Article
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