Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1990-4-26
pubmed:abstractText
Using two-dimensional and M-mode echocardiography, mitral valve function was assessed during mechanical cardiopulmonary resuscitation (CPR). In 10 anesthetized pigs CPR began 1 min after induction of ventricular fibrillation; in all pigs three different compressive forces (200, 350, and 500 Newton [N]) were applied in randomized sequence for 3 min each, thus resulting in a reduction of anterior-posterior chest diameter by 15%, 20%, and 25%, respectively. Echocardiographic recordings of adequate technical quality were obtained from seven animals. During ventricular fibrillation, mitral valve leaflets showed fibrillatory movements without closure. During CPR systole with a compressive force of 200 N, the mitral valve closed in 114 of 700 CPR cycles (16%). This rate increased significantly (P less than 0.001) to 399 of 584 cycles (68%) with 350 N, and further to 470 of 494 cycles (95%) with 500 N. The higher mitral valve closure incidence was linked to statistically significant increases in systolic cerebral (+125%) and diastolic myocardial perfusion pressures (+136%) and cardiac output. We thus conclude that with low compressive force blood flow during mechanical CPR is due mainly to the chest pump mechanism, whereas the cardiac pump mechanism is effective with high compressive forces.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0003-2999
pubmed:author
pubmed:issnType
Print
pubmed:volume
70
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
350-6
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Echocardiographic assessment of mitral valve function during mechanical cardiopulmonary resuscitation in pigs.
pubmed:affiliation
Ludwig Boltzmann Institute of Experimental Anesthesia and Research in Intensive Care Medicine, Vienna, Austria.
pubmed:publicationType
Journal Article